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clm-027r6qe8a5

SNc (Substantia nigra, compact part) projects to MY (Medulla)

All claims for this connection
Species
Rat
Result
absent
Method
retrograde tracer
Sign
unknown
Evidence
Despite widespread rostral appearance of the medulla-derived human alpha-synuclein, no labelling was found in the substantia nigra pars compacta and dopaminergic cell numbers were unchanged; the authors attribute this to the lack of a direct anatomical link between the SNc and the medulla.
Source

Caudo‐rostral brain spreading of α‐synuclein through vagal connections

EMBO Molecular Medicine, 2013

DOI 10.1002/emmm.201302475 · PubMed 23703938 · PMC3721477, Results (SNc paragraph); Discussion

Licence: CC-BY-3.0

Named in the paper
“substantia nigra pars compacta (SNc)” and “medulla oblongata (MO)”
Made by
an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by

a second AI model (claude-opus-5) agrees, 2026-10-09

“The paper reports no hα-syn labelling and unchanged dopaminergic counts in SNc and attributes this to lack of direct SNc–medulla connections.”

Status

proposed

Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.