clm-17wnw4g7pt
ACA (Anterior cingulate area) functionally connects to BLA (Basolateral amygdalar nucleus)
All claims for this connection- Species
- Mouse
- Result
- present
- Method
- optogenetic circuit mapping
- Sign
- excitatory
- Evidence
- Light activation of ChR2-expressing ACC axons in slices evoked short-latency PSPs in BLA neurons. The PSPs persisted in TTX plus 4-AP, consistent with a monosynaptic input, and were abolished by NBQX plus APV, showing they are glutamatergic. Results were replicated in wild-type mice with CaMKIIa-ChR2 in the ACC.
- Measurements
- connection probability: 0.71, n = 17
- connection probability: 0.79, n = 14
- conduction delay: 6.4 ms (SEM 0.7), n = 12
- Source
Anterior cingulate cortex and its input to the basolateral amygdala control innate fear response
Nature Communications, 2018
DOI 10.1038/s41467-018-05090-y · PubMed 30013065 · PMC6048069, Fig. 5i-n; Supplementary Fig. 5a-iLicence: CC-BY-4.0
- Named in the paper
- “ACC” and “BLA”
- Made by
- an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-09
- Checked by
a second AI model (claude-opus-5-5) agrees, 2026-10-09
“Slice recordings show 12/17 and 11/14 BLA cells responding, a 6.4 ± 0.7 ms latency (n = 12), persistence in TTX/4-AP and block by NBQX/APV, which supports an excitatory monosynaptic input.”
- Status
proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.