clm-2set4p7jnx
sAMY (Striatum-like amygdalar nuclei) functionally connects to LHA (Lateral hypothalamic area)
All claims for this connection- Species
- Mouse
- Result
- present
- Method
- optogenetic circuit mapping
- Sign
- inhibitory
- Evidence
- Optical activation of ChR2-expressing amygdala VGAT axon terminals produced short-latency currents in MCH neurons that reversed near chloride equilibrium, indicating direct GABAergic inhibition; mean amplitude about 115 pA.
- Measurements
- connection probability: 0.38, n = 13
- conduction delay: 3.66 ms (SEM 0.27), n = 5
- Source
Awake dynamics and brain-wide direct inputs of hypothalamic MCH and orexin networks
Nature Communications, 2016
DOI 10.1038/ncomms11395 · PubMed 27102565 · PMC4844703, Fig. 6d,eLicence: CC-BY-4.0
- Named in the paper
- “amygdala VGAT neurons (central and medial areas)” and “LH MCH neurons”
- Made by
- an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-09
- Checked by
a second AI model (claude-opus-5-5) agrees, 2026-10-09
“5 of 13 amygdala cells were connected, with latency 3.66±0.27 ms (n=5), about 115 pA and reversal near chloride; the injection covered central and medial amygdala.”
- Status
proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.