clm-40bf534ep2

CEA (central amygdaloid nucleus) functionally connects to AI (Agranular insular area)

Species: Rat
Result: present
Method: optogenetic circuit mapping
Sign: unknown
Evidence: CeA ChR2 stimulation was followed by increased Fos in far-posterior insular cortex (over 500% above baseline in the sucrose/cocaine group and over 250% above eYFP controls in the shock-rod group).
Source: The central amygdala recruits mesocorticolimbic circuitry for pursuit of reward or pain
Nature Communications, 2020
DOI 10.1038/s41467-020-16407-1 · PubMed 32483118 · PMC7264246, Results, 'Shock-rod attraction activates mesocorticolimbic circuity'; Fig. 5
Licence: CC-BY-4.0
Named in the paper: “central nucleus of amygdala (CeA)” and “posterior insula”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5) agrees, 2026-10-09
“Posterior insula Fos elevations (>500% reward group, >250% over eYFP in shock-rod group) are stated in the results.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.