clm-7772d2k140
CEAl PKC-delta-expressing neurons functionally connects to ZI (Zona incerta)
All claims for this connection- Species
- Mouse
- Result
- ambiguous
- Method
- optogenetic circuit mapping
- Sign
- unknown
- Evidence
- In mice with cre-dependent ChR2 in PKCδ central amygdala neurons, whole-cell recordings from 30 zona incerta neurons across 8 mice yielded no light-evoked postsynaptic currents despite robust terminal labelling, leaving the monosynaptic PKCδ-to-ZI connection unresolved.
- Measurements
- connection probability: 0, n = 30
- Source
An inhibitory circuit from central amygdala to zona incerta drives pain-related behaviors in mice
eLife, 2022
DOI 10.7554/elife.68760 · PubMed 36269044 · PMC9635874, Author response (attempted cre-dependent ChR2 recordings)Licence: CC0-1.0
- Named in the paper
- “CeA-PKCδ neurons” and “ZI”
- Made by
- an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-10
- Checked by
a second AI model (claude-opus-5) agrees, 2026-10-10
“The author response describes 30 recorded ZI neurons from 8 PKCδ-cre mice with no optically evoked responses, deemed inconclusive.”
- Status
proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.