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BLA (basal amygdaloid nucleus) functionally connects to CA1 (Field CA1)

All claims for this connection

Species: Rat
Result: present
Method: optogenetic circuit mapping
Sign: unknown
Evidence: Blue-light stimulation of channelrhodopsin-expressing putative glutamatergic BLA neurons in freely moving rats evoked frequency-matched LFP responses in CA1 at 8, 20, 50 and 50/8 Hz, whereas control near-infrared light evoked no response. The CA1 peak followed the first light pulse at 12.7 ms versus 6.67 ms in the BLA (a 6.03 ms lag, interpreted as a monosynaptic BLA-to-CA1 drive); latencies after the final pulse were 14.0, 19.3, 16.0 and 9.33 ms for the 8, 20, 50 and 50/8 Hz conditions. Stimulation at 50 and 50/8 Hz significantly raised CA1 slow gamma power, and only 50/8 Hz stimulation significantly increased CA1 theta-gamma comodulation.
Measurements: conduction delay: 12.7 ms, n = 5
Source: Optogenetic Stimulation of the Basolateral Amygdala Increased Theta-Modulated Gamma Oscillations in the Hippocampus
Frontiers in Behavioral Neuroscience, 2019
DOI 10.3389/fnbeh.2019.00087 · PubMed 31114488 · PMC6503755, Figs. 2, 3, 4, 5, 6; Results sections on 1-s and 5-s stimulation
Licence: CC-BY-4.0
Named in the paper: “BLA” and “CA1 (pyramidal layer of intermediate hippocampus)”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-10
Checked by: a second AI model (claude-opus-5-5) disagrees, 2026-10-10
“The 12.7 ms value is the CA1 latency to peak from light onset, not a conduction delay; the BLA-to-CA1 lag the paper reports is 6.03 ms.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.