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DR (Dorsal nucleus raphe) projects to CEA (central amygdaloid nucleus)

All claims for this connection
Species
Rat
Result
present
Method
retrograde tracer
Sign
unknown
Evidence
Retrograde AAV-CAG-tdTomato injected into the central amygdala labelled dorsal raphe neurons, distributed across DRN subdivisions rostrally and along the ventromedial midline caudally; about 80% of these labelled DRN neurons were Tph2-positive and roughly 40% were nNOS-positive.
Measurements
  • fraction of labelled neurons: 0.8
Source

Chemogenetic inhibition of prefrontal cortex inputs to dorsal raphe reduces anxiety behaviors in male rat model of fetal alcohol spectrum disorder

Scientific Reports, 2025

DOI 10.1038/s41598-025-99181-8 · PubMed 40275074 · PMC12022358, Fig. 4A–D; Fig. 6A–C

Licence: CC-BY-NC-ND-4.0

Named in the paper
“DRN” and “CeA”
Made by
an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by

a second AI model (claude-opus-5) agrees, 2026-10-09

“Retrograde tdTomato from CeA labelled DRN neurons, ~80% Tph2+ and ~40% nNOS+, as described in Figs 4 and 6.”

Status

proposed

Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.