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clm-9hr631paa9

AIp (Agranular insular area, posterior part) projects to ACB (Nucleus accumbens)

All claims for this connection
Species
Mouse
Result
present
Method
anterograde tracer
Sign
unknown
Strength
strong
Evidence
Dense axonal fibers from pIC glutamatergic neurons were seen in the nucleus accumbens core.
Source

Linking emotional valence and anxiety in a mouse insula-amygdala circuit

Nature Communications, 2023

DOI 10.1038/s41467-023-40517-1 · PubMed 37604802 · PMC10442438, Fig. 3e; Supplementary Fig. 3f-g

Licence: CC-BY-4.0

Named in the paper
“pIC” and “nucleus accumbens core (NAc)”
Made by
an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-09
Checked by

a second AI model (claude-opus-5-5) agrees, 2026-10-09

“The text reports dense pIC axonal fibers in the NAc core, citing Fig. 3e and Supplementary Fig. 3f-g.”

Status

proposed

Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.