clm-aq89rntp6z

BLAa (Basolateral amygdalar nucleus, anterior part) functionally connects to BST (Bed nuclei of the stria terminalis)

Species: Mouse
Result: present
Method: optogenetic circuit mapping
Sign: excitatory
Evidence: Light activation of ChR2-expressing anterior BLA terminals in dorsal BNST raised the tonic firing rate of adBNST neurons, and evoked monosynaptic excitatory currents (TTX-blocked, 4-AP-restored) whose amplitude exceeded the accompanying disynaptic inhibitory currents; chemogenetic activation of aBLA to dBNST neurons likewise increased adBNST calcium signals in vivo.
Source: Synergism between two BLA-to-BNST pathways for appropriate expression of anxiety-like behaviors in male mice
Nature Communications, 2024
DOI 10.1038/s41467-024-47966-2 · PubMed 38658548 · PMC11043328, Fig. 2b–d; Fig. 3a, b, d; Supplementary Fig. 3b, c
Licence: CC-BY-4.0
Named in the paper: “aBLA” and “adBNST”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5) agrees, 2026-10-09
“aBLA input activation increased adBNST firing with excitation exceeding inhibition and in vivo calcium rise.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.