clm-ar2fmfj9gd

ILA (Infralimbic area) functionally connects to BLN (basolateral amygdaloid nuclear complex)

All claims for this connection

Species: Rat
Result: present
Method: electrical stimulation
Sign: unknown
Evidence: Bipolar electrical stimulation of the medial prefrontal cortex (electrode in infralimbic cortex, possible spread to prelimbic) reliably evoked single spikes in putative projection neurons of the lateral and basolateral amygdala in anesthetized rats; 11 responsive neurons were found in Exp 1 and 9 in Exp 2. Only units with onset latencies under 30 ms, little latency shift with increasing intensity and low jitter were kept, which the authors take as monosynaptic and not antidromic; stimulus current was titrated so that baseline evoked spike probability was about 0.5 of 50 trials (49.3 ± 3.6% before and 50.3 ± 7.6% after drug application in 6 neurons).
Source: Lateral Orbitofrontal Cortical Modulation on the Medial Prefrontal Cortex-Amygdala Pathway: Differential Regulation of Intra-Amygdala GABAA and GABAB Receptors
International Journal of Neuropsychopharmacology, 2017
DOI 10.1093/ijnp/pyx027 · PubMed 28444246 · PMC5492808, Methods (electrically evoked responses); Results Exp 1 and 2; Fig. 2A, Fig. 3A
Named in the paper: “medial prefrontal cortex (mPFC; IL, possible PL spread)” and “LA/BLA”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5) agrees, 2026-10-09
“Paper's own recordings show mPFC stimulation evoking short-latency spikes in LA/BLA neurons in rats, with the cited neuron counts and baseline probabilities.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.