clm-cz2ms78e6t

CA1 (Field CA1) functionally connects to BLA (Basolateral amygdalar nucleus)

Species: Mouse
Result: present
Method: optogenetic circuit mapping
Sign: excitatory
Evidence: Photostimulation of ventral CA1 axons evoked monophasic EPSPs in BA interneurons (pooled with intercalated cells), and it evoked spiking at lower light power than in principal neurons. Theta burst stimulation increased interneuron firing both in vivo and ex vivo.
Measurements: connection probability: 0.61, n = 44
Source: Hippocampal Theta Input to the Amygdala Shapes Feedforward Inhibition to Gate Heterosynaptic Plasticity
Neuron, 2015
DOI 10.1016/j.neuron.2015.08.024 · PubMed 26402610 · PMC4590554, Figs. 2F-G, 3D-F, 4D-F, 5F
Licence: CC-BY-4.0
Named in the paper: “vCA1 pyramidal cell axons” and “BA interneurons (INs) and ITCs”
Made by: an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5) agrees, 2026-10-09
“Light-evoked EPSPs in 27/44 INs/ITCs plus lower spike threshold and TBS-driven firing support excitatory vCA1 input.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.