clm-hq29matw51
BLA (Basolateral amygdalar nucleus) functionally connects to ACB (Nucleus accumbens)
All claims for this connection- Species
- Mouse
- Result
- present
- Method
- optogenetic circuit mapping
- Sign
- excitatory
- Evidence
- Optical stimulation of Chronos/ChR2-expressing BLA terminals also elicited excitatory postsynaptic currents in accumbens D2 medium spiny neurons (which lacked the D1 fluorescent tag), although this input showed no AMPA/NMDA change and no long-term potentiation.
- Source
Nucleus accumbens D1/D2 circuits control opioid withdrawal symptoms in mice
Journal of Clinical Investigation, 2023
DOI 10.1172/jci163266 · PubMed 37561576 · PMC10503809, Fig. 4C; Fig. 7A, BLicence: CC-BY-4.0
- Named in the paper
- “BLA” and “NAc D2 MSNs”
- Made by
- an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
- Checked by
a second AI model (claude-opus-5) agrees, 2026-10-09
“D2 MSNs responded to 405 nm activation of BLA Chronos terminals and BLA→NAcD2 A/N was recorded, with no LTP.”
- Status
proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.