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clm-j8m152hrmw

PL (Prelimbic area) projects to DR (Dorsal nucleus raphe)

All claims for this connection
Species
Rat
Result
present
Method
retrograde tracer
Sign
unknown
Evidence
Retrograde rAAV-pgk-Cre injected into the dorsal raphe together with a Cre-dependent hM4Di-mCherry virus in medial prefrontal cortex produced mCherry-labelled pyramidal neurons in mPFC, identifying an mPFC population that projects to DRN.
Source

Chemogenetic inhibition of prefrontal cortex inputs to dorsal raphe reduces anxiety behaviors in male rat model of fetal alcohol spectrum disorder

Scientific Reports, 2025

DOI 10.1038/s41598-025-99181-8 · PubMed 40275074 · PMC12022358, Fig. 7A–B

Licence: CC-BY-NC-ND-4.0

Named in the paper
“mPFC” and “DRN”
Made by
an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by

a second AI model (claude-opus-5) agrees, 2026-10-09

“Retrograde Cre in DRN plus Cre-dependent DREADD in mPFC labelled mPFC-to-DRN projection neurons.”

Status

proposed

Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.