clm-m95wr57jfd
PL (Prelimbic area) functionally connects to BLA glutamatergic principal neurons
All claims for this connection- Species
- Mouse
- Result
- present
- Method
- optogenetic circuit mapping
- Sign
- excitatory
- Evidence
- Blue-light activation of ChR2-expressing dmPFC terminals in the basal amygdala evoked monosynaptic AMPA- and NMDA-receptor-mediated EPSCs in BA principal neurons recorded in whole-cell mode; EPSCs persisted with GABA-A blockade by bicuculline, and paired-pulse ratio, input-output and AMPA/NMDA ratio were measured at this synapse.
- Source
Deletion of NRXN1α impairs long-range and local connectivity in amygdala fear circuit
Translational Psychiatry, 2020
DOI 10.1038/s41398-020-00926-y · PubMed 32684634 · PMC7370229, Figs. 1a, d–i; 2a–c; 3a–cLicence: CC-BY-4.0
- Named in the paper
- “dmPFC” and “BA principal neurons”
- Made by
- an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
- Checked by
a second AI model (claude-opus-5) agrees, 2026-10-09
“Light activation of dmPFC terminals evoked glutamatergic EPSCs in BA principal cells in the cited figures.”
- Status
proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.