clm-mcjx7gqmxp

MH (Medial habenula) synapses onto VTA (Ventral tegmental area)

Species: Mouse
Result: present
Method: transsynaptic tracer
Sign: unknown
Evidence: Medial habenula neurons were labelled as inputs to VTA dopamine cells; this input was reduced in brains from mice given a single addictive drug exposure.
Source: Drug-induced changes in connectivity to midbrain dopamine cells revealed by rabies monosynaptic tracing
eLife, 2026
DOI 10.7554/elife.93664 · PubMed 42138352 · PMC13179063, Fig. 1C, Fig. 3G, Fig. 5K
Licence: CC-BY-4.0
Named in the paper: “MHb” and “VTADA cells (DAT-Cre VTA dopamine neurons)”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-10
Checked by: a second AI model (claude-opus-5) agrees, 2026-10-10
“MHb is a quantified input described as reduced in drug-treated brains and a negative PC2 weight.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.