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clm-nys0bn9met

LC (Locus ceruleus) projects to MY (Medulla)

All claims for this connection
Species
Rat
Result
present
Method
retrograde tracer
Sign
unknown
Evidence
Human alpha-synuclein expressed only in medullary neurons was later found in axonal fibres within the pontine coeruleus–subcoeruleus complex, some of which were also tyrosine hydroxylase positive, taken as evidence of protein transfer along the direct projection these cells send to the medulla.
Source

Caudo‐rostral brain spreading of α‐synuclein through vagal connections

EMBO Molecular Medicine, 2013

DOI 10.1002/emmm.201302475 · PubMed 23703938 · PMC3721477, Fig 2E,F; Supporting Information Fig S3

Licence: CC-BY-3.0

Named in the paper
“coeruleus–subcoeruleus complex” and “medulla oblongata (MO)”
Made by
an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by

a second AI model (claude-opus-5) agrees, 2026-10-09

“Coeruleus–subcoeruleus fibres with hα-syn, some TH-positive, are reported (Fig 2F, Fig S3).”

Status

proposed

Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.