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PVH (Paraventricular hypothalamic nucleus) projects to PL (Prelimbic area)

All claims for this connection
Species
Mouse
Result
present
Method
retrograde tracer
Sign
unknown
Evidence
Retrograde AAV-hSyn-EGFP injected into the prelimbic cortex labelled neurons in the paraventricular hypothalamic nucleus; retrograde Cre viruses (hSyn-Cre or OXT-Cre) delivered to PL also drove Cre-dependent expression in PVN neurons, including oxytocinergic ones.
Source

Medial prefrontal cortex neurons integrate amygdala and hypothalamic oxytocin signals to mediate stress-induced social alterations

Communications Biology, 2026

DOI 10.1038/s42003-026-10089-z · PubMed 42026195 · PMC13316100, Fig. 3e; Fig. 5a, g

Licence: CC-BY-NC-ND-4.0

Named in the paper
“PVN” and “PL”
Made by
an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by

a second AI model (claude-opus-5) agrees, 2026-10-09

“Retro-AAV in PL labelled PVN neurons, and retrograde Cre viruses drove PVN expression.”

Status

proposed

Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.