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PVH (Paraventricular hypothalamic nucleus) projects to ACB (Nucleus accumbens)

Species: Mouse
Result: present
Method: retrograde tracer
Sign: unknown
Evidence: A retrograde virus placed in the nucleus accumbens labelled oxytocin-immunoreactive neurons in the paraventricular hypothalamic nucleus, and these NAc-projecting OXT cells occupied a territory separate from the CeA-projecting ones.
Source: Distinct projections of PVN oxytocin neurons regulate the divergent defensive behaviors in response to social threat
Science Advances, 2026
DOI 10.1126/sciadv.aeb0400 · PubMed 42341137 · PMC13292991, fig. S3, A to E
Named in the paper: “PVN” and “NAc”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5) agrees, 2026-10-09
“Retrograde virus in NAc labeled OXT-immunostained PVN neurons, segregated from CeA-projecting ones.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.