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PL (Prelimbic area) projects to BLA (Basolateral amygdalar nucleus)

All claims for this connection
Species
Mouse
Result
present
Method
retrograde tracer
Sign
unknown
Evidence
A retrograde AAV carrying InteinC-CreC injected into the BLA reconstituted Cre only in neurons whose axons reach the BLA, producing tdTomato-positive somata in the prelimbic cortex, showing that prelimbic neurons send axons to the BLA.
Source

Neural circuit pathology driven by Shank3 mutation disrupts social behaviors

Cell Reports, 2022

DOI 10.1016/j.celrep.2022.110906 · PubMed 35675770 · PMC9210496, Figures 1B, 1D; Results, 'Shank3 mutation in the PFC-BLA neural circuit'

Licence: CC-BY-NC-ND-4.0

Named in the paper
“PFC (prelimbic, PL)” and “BLA”
Made by
an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by

a second AI model (claude-opus-5) agrees, 2026-10-09

“Retrograde AAV in BLA produced tdTomato somata in PL, establishing the projection.”

Status

proposed

Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.