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clm-s2dmme0j1r

CL:0000207 functionally connects to PERI (Perirhinal area)

All claims for this connection
Species
Mouse
Result
present
Method
optogenetic circuit mapping
Sign
unknown
Evidence
Optogenetic activation of channelrhodopsin-expressing olfactory sensory neurons in the nasal cavity changed perirhinal local field potential high-gamma power in a frequency-dependent way (increase at 2 Hz, decrease at 7 Hz) and, by fibre photometry, produced corresponding increases or decreases in calcium activity of perirhinal parvalbumin interneurons.
Source

A nose-to-brain circuit underlies anxiety regulation by nasal afferent frequency in mice

Proceedings of the National Academy of Sciences, 2026

DOI 10.1073/pnas.2603853123 · PubMed 42611993 · PMC13506056, Fig. 2 A–C; Fig. 3 C–F

Licence: CC-BY-NC-ND-4.0

Named in the paper
“olfactory sensory neurons (OSNs)” and “PRC”
Made by
an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by

a second AI model (claude-opus-5) agrees, 2026-10-09

“Optogenetic OSN stimulation frequency-dependently altered PRC high-gamma and PRC PV calcium activity.”

Status

proposed

Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.