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CEA (central amygdaloid nucleus) functionally connects to SNc (Substantia nigra, compact part)

All claims for this connection
Species
Rat
Result
present
Method
optogenetic circuit mapping
Sign
unknown
Evidence
After CeA ChR2 stimulation paired with shock-rod encounters, Fos expression in substantia nigra pars compacta was raised roughly 200% above eYFP control levels, consistent with recruitment of midbrain dopamine neurons by CeA activation.
Source

The central amygdala recruits mesocorticolimbic circuitry for pursuit of reward or pain

Nature Communications, 2020

DOI 10.1038/s41467-020-16407-1 · PubMed 32483118 · PMC7264246, Results, 'Shock-rod attraction activates mesocorticolimbic circuity'; Fig. 5

Licence: CC-BY-4.0

Named in the paper
“central nucleus of amygdala (CeA)” and “substantia nigra pars compacta (SNc)”
Made by
an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by

a second AI model (claude-opus-5) agrees, 2026-10-09

“SNc Fos >200% elevation after CeA ChR2 shock-rod pairing is reported and statistically significant.”

Status

proposed

Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.