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clm-vd8xgvg01e

PVH (Paraventricular hypothalamic nucleus) projects to BST (Bed nuclei of the stria terminalis)

All claims for this connection
Species
Mouse
Result
present
Method
anterograde tracer
Sign
unknown
Evidence
Fluoro-Ruby placed in the PVN produced labelled axons in the BnST of B6 mice; the same injection in BTBR mice yielded much weaker terminal labelling there, which the authors interpret as degraded PVN-to-BnST projections in the autism model strain (n = 4 per strain).
Source

Functional disruption of oxytocin projections participates atypical social and anxiety-like behaviours in BTBR mouse model of autism

Open Biology, 2025

DOI 10.1098/rsob.240387 · PubMed 40858267 · PMC12380489, Fig. 5D; Results, 'Oxytocin neural projection patterns reveal strain difference'

Licence: CC-BY-4.0

Named in the paper
“PVN” and “BnST”
Made by
an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by

a second AI model (claude-opus-5) agrees, 2026-10-09

“Fluoro-Ruby anterograde tracing from PVN showed BnST labelling in B6 and diminished signal in BTBR, n=4 each.”

Status

proposed

Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.