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ILA (Infralimbic area) projects to BLA (Basolateral amygdalar nucleus)

All claims for this connection
Species
Mouse
Result
present
Method
retrograde tracer
Sign
unknown
Strength
strong
Evidence
Cholera toxin B injected into the BLA retrogradely labelled many neurons in the infralimbic cortex, in both layer 2/3 and layer 5, with labelling described as dense and concentrated in superficial IL layers; of all labelled PFC cells, 38.2% were BLA-labelled and only 3.4% were double-labelled with NAc tracer. Retrobeads and a retrograde HSV-Cre placed in the BLA likewise labelled IL neurons that were then recorded or chemogenetically targeted.
Source

Fear extinction requires infralimbic cortex projections to the basolateral amygdala

Translational Psychiatry, 2018

DOI 10.1038/s41398-018-0106-x · PubMed 29507292 · PMC5838104, Fig. 1a–d; Fig. 2a; Fig. 4a–b; Results, 'Separate IL and PL projections to BLA and NAc'

Licence: CC-BY-4.0

Named in the paper
“IL” and “BLA”
Made by
an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by

a second AI model (claude-opus-5) agrees, 2026-10-09

“BLA retrograde tracing labelled IL neurons (38.2%, 3.4% double-labelled), matching the paper.”

Status

proposed

Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.