clm-w25bgrekbk
DR (Dorsal nucleus raphe) functionally connects to BLA (Basolateral amygdalar nucleus)
All claims for this connection- Species
- Mouse
- Result
- present
- Method
- optogenetic circuit mapping
- Sign
- modulatory
- Evidence
- With glutamate receptors blocked by kynurenic acid, 30 s trains of light at 20 Hz evoked a slow inward (excitatory) current in about half of basal amygdala interneurons, which was abolished by the 5-HT2A antagonist MDL 100907 and grew with increasing stimulation frequency.
- Measurements
- connection probability: 0.53, n = 59
- Source
Control of Amygdala Circuits by 5-HT Neurons via 5-HT and Glutamate Cotransmission
The Journal of Neuroscience, 2017
DOI 10.1523/jneurosci.2238-16.2016 · PubMed 28087766 · PMC5320609, Fig. 3A–C; Fig. 4ALicence: CC-BY-NC-SA-4.0
- Named in the paper
- “DRN (5-HT neurons)” and “BA interneurons (INs)”
- Made by
- an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-10
- Checked by
a second AI model (claude-opus-5) agrees, 2026-10-10
“53% of 59 INs showed a 5-HT2A-mediated slow EPSC increasing with frequency under kynurenic acid.”
- Status
proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.