clm-w3x4nmwrq0

VTA (Ventral tegmental area) projects to PL (Prelimbic area)

Species: Mouse
Result: present
Method: retrograde tracer
Sign: unknown
Evidence: Retrograde CAV2-FLEx-Flp delivered to medial prefrontal cortex recombined in Cre-positive VTA dopamine neurons, defining a VTADA→mPFC population and showing that VTA dopamine cells project to medial prefrontal cortex.
Source: Drug-induced changes in connectivity to midbrain dopamine cells revealed by rabies monosynaptic tracing
eLife, 2026
DOI 10.7554/elife.93664 · PubMed 42138352 · PMC13179063, Fig. 7—figure supplement 2E–H; Methods (cTRIO, mPFC injections)
Licence: CC-BY-4.0
Named in the paper: “VTADA” and “mPFC”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-10
Checked by: a second AI model (claude-opus-5) is unsure, 2026-10-10
“The paper specifies only mPFC as the retrograde injection site, so the prelimbic-specific assignment is not established.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.