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AI (Agranular insular area) projects to CEA (central amygdaloid nucleus)

All claims for this connection
Species
Rat
Result
present
Method
retrograde tracer
Sign
unknown
Evidence
AAV2-retro vectors placed in the central amygdala retrogradely labelled neurons in the anterior agranular insula, mostly in layers II and V, with these cells making up 58% of the labelled amygdala-projecting insular population and being more numerous in the ventral agranular insula. The same projection was targeted by injecting a retrograde Cre vector into the central amygdala together with Cre-dependent DREADD vectors in the insula.
Measurements
  • fraction of labelled neurons: 0.58
Source

Chemogenetic Stimulation and Silencing of the Insula, Amygdala, Nucleus Accumbens, and Their Connections Differentially Modulate Alcohol Drinking in Rats

Frontiers in Behavioral Neuroscience, 2020

DOI 10.3389/fnbeh.2020.580849 · PubMed 33328918 · PMC7671963, Figs. 5A–C; Fig. 4A

Licence: CC-BY-4.0

Named in the paper
“agranular insula (AID, AIV)” and “central amygdala (CeA)”
Made by
an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-10
Checked by

a second AI model (claude-opus-5) agrees, 2026-10-10

“Paper reports 58% of amygdala-projecting agranular insula neurons labelled from central amygdala, with ventral predominance.”

Status

proposed

Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.