clm-wt5qg9yw78

MPO (Medial preoptic area) synapses onto PAG (Periaqueductal gray)

Species: Mouse
Result: present
Method: transsynaptic tracer
Sign: unknown
Evidence: Pseudotyped rabies tracing from CANE-tagged PAG-USV neurons and from VGAT+ caudo/ventrolateral PAG neurons labelled cell bodies in the medial preoptic area, indicating monosynaptic preoptic input to both PAG cell types. In situ hybridization showed about 84% of these labelled preoptic cells express VGAT.
Source: Circuit and synaptic organization of forebrain-to-midbrain pathways that promote and suppress vocalization
eLife, 2020
DOI 10.7554/elife.63493 · PubMed 33372655 · PMC7793624, Fig. 1A–B; Fig. 1—figure supplement 1A
Licence: CC-BY-4.0
Named in the paper: “preoptic area of the hypothalamus (POA)” and “PAG-USV neurons and GABAergic PAG neurons”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-10
Checked by: a second AI model (claude-opus-5-5) agrees, 2026-10-10
“Medial POA neurons were labelled from both PAG cell types, and about 84% were GABAergic.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.