clm-xakja64yve

Rat central amygdala corticotropin-releasing hormone-expressing neurons projects to LC (Locus ceruleus)

Species: Rat
Result: present
Method: anterograde tracer
Sign: unknown
Strength: strong
Evidence: mCherry-labelled axons from CeL CRF neurons were among the largest and densest projections and reached the locus coeruleus, running orthogonally to the dendrites of tyrosine-hydroxylase-positive LC neurons.
Source: A Transgenic Rat for Investigating the Anatomy and Function of Corticotrophin Releasing Factor Circuits
Frontiers in Neuroscience, 2015
DOI 10.3389/fnins.2015.00487 · PubMed 26733798 · PMC4689854, Fig. 3B-D
Named in the paper: “CeL CRF neurons” and “locus coeruleus (LC)”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-10
Checked by: a second AI model (claude-opus-5) agrees, 2026-10-10
“Dense labelled fibers reached LC, interdigitated orthogonally with TH-positive dendrites.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.