clm-xtsng0e9n3

CA3 (Field CA3) functionally connects to CA1 (Field CA1)

Species: Mouse
Result: present
Method: electrical stimulation
Sign: excitatory
Evidence: In acute hippocampal slices, bipolar stimulation of the Schaffer collateral fibers evoked field excitatory postsynaptic potentials in the CA1 stratum radiatum, and theta-burst stimulation of these afferents induced long-term potentiation, which was compared between young and aged mice treated with a beta2-adrenergic antagonist.
Source: Beta2 adrenergic receptor–mediated abnormal myelopoiesis drives neuroinflammation in aged patients with traumatic brain injury
Science Advances, 2024
DOI 10.1126/sciadv.adp5239 · PubMed 39028822 · PMC11259178, Fig. 7, G to I; Methods, field recordings
Named in the paper: “Schaffer collateral (CA3)” and “CA1”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5) agrees, 2026-10-09
“The paper's own slice recordings show stimulation of Schaffer collateral afferents evoking excitatory fEPSPs and LTP in CA1 of mice, matching the locator.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.