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Isocortex projects to PSTN (Parasubthalamic nucleus)

Species: Mouse
Result: present
Method: retrograde tracer
Sign: unknown
Evidence: CTB injected into the ipsilateral posterior lateral hypothalamus including the PSTh labeled DgI cells mostly in L5b, nearly all CTIP2-positive. None of these cells were double-labeled with CTB from the contralateral CeA.
Source: Dissection of insular cortex layer 5 reveals two sublayers with opposing modulatory roles in appetitive drinking behavior
iScience, 2023
DOI 10.1016/j.isci.2023.106985 · PubMed 37378339 · PMC10291511, Fig. 2B-H
Licence: CC-BY-4.0
Named in the paper: “DgI L5b population (CTIP2+)” and “ipsilateral PSTh”
Made by: an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5-5) agrees, 2026-10-09
“PSTh-ipsi CTB labeled mainly L5b cells, 98.1% CTIP2-positive, with no cells double-labeled from the contralateral CeA.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.