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PL (Prelimbic area) functionally connects to BLA glutamatergic principal neurons
All claims for this connection- Species
- Mouse
- Result
- present
- Method
- electrical stimulation
- Sign
- excitatory
- Evidence
- In slices where the PL-to-BLA pathway was preserved, BLA pyramidal neurons of sgTmem74 mice fired more action potentials; this hyperexcitability disappeared in slices in which the PL-BLA connection was severed, implying functional excitatory drive from PL onto BLA pyramidal neurons.
- Source
Divergent projections of the prelimbic cortex mediate autism- and anxiety-like behaviors
Molecular Psychiatry, 2023
DOI 10.1038/s41380-023-01954-y · PubMed 36690791 · PMC10611563, Supplementary Fig. 5d–jLicence: CC-BY-4.0
- Named in the paper
- “PL” and “PNs of the BLA”
- Made by
- an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
- Checked by
a second AI model (claude-opus-5) disagrees, 2026-10-09
“The evidence was slice preparation preserving versus severing the pathway with whole-cell recording, not electrical stimulation.”
- Status
proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.