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clm-zh439re61e

LC (Locus ceruleus) projects to BLA (basal amygdaloid nucleus)

All claims for this connection
Species
Rat
Result
present
Method
retrograde tracer
Sign
unknown
Evidence
Retrograde virus injected into the BLA labelled locus coeruleus neurons, and in a separate experiment a retrograde Cre virus in the BLA combined with a TH-dependent construct in the LC allowed selective targeting of LC neurons projecting to the BLA; LC-labelled cells were c-Fos positive after both CS and US retrieval of remote fear memory.
Source

A ventral hippocampus-basolateral amygdala circuit regulates the unconditioned stimulus retrieval-induced reconsolidation of remote fear memory

Journal of Advanced Research, 2026

DOI 10.1016/j.jare.2025.10.015 · PubMed 41086982 · PMC13316356, Fig. 4b, 4e; Fig. 6i

Licence: CC-BY-NC-ND-4.0

Named in the paper
“LC” and “BLA”
Made by
an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by

a second AI model (claude-opus-5) agrees, 2026-10-09

“BLA retrograde tracing labelled LC neurons activated after both retrieval types, and retro-Cre in BLA targeted LC→BLA cells.”

Status

proposed

Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.