clm-zy5f5gfp18

CEA (Central amygdalar nucleus) projects to PAG (Periaqueductal gray)

Species: Mouse
Result: ambiguous
Method: retrograde tracer
Sign: unknown
Evidence: AAV-retro-Cre injected into the caudolateral PAG of a Cre-dependent tdTomato reporter mouse produced no cell body labelling in the central amygdala, but the authors attribute this to restricted tropism of the retrograde AAV rather than to an absent projection, since rabies tracing did label CeA neurons.
Source: Circuit and synaptic organization of forebrain-to-midbrain pathways that promote and suppress vocalization
eLife, 2020
DOI 10.7554/elife.63493 · PubMed 33372655 · PMC7793624, Fig. 4—figure supplement 2
Licence: CC-BY-4.0
Named in the paper: “CeA” and “caudolateral PAG”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-10
Checked by: a second AI model (claude-opus-5-5) agrees, 2026-10-10
“Retro-AAV did not label the CeA, which the authors attribute to viral tropism, so the result is ambiguous.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.