Mouse

LC (Locus ceruleus) projects to BLA (Basolateral amygdalar nucleus)

2 claims from 1 source: 2 found, 0 tested and absent, 0 ambiguous. Evidence: anterograde tracer, retrograde tracer. Strongest reported: strong.

The claims behind it

clm-crr4mq7pz3presentretrograde tracerstrength: strongproposed

Fluorogold injected into the BLA retrogradely labelled many neurons in the posterior locus coeruleus, and these cells were immunopositive for the norepinephrine transporter.

DOI 10.1172/jci.insight.161874 · PubMed 37200091 · PMC10371239, Fig. 6A–C

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

clm-w6mnfy4ap3presentanterograde tracerproposed

Cre-dependent helper AAV (FLEX-TVA-GFP) injected into the LC of DBH-Cre mice produced GFP-labelled axonal fibres in the BLA, showing that noradrenergic LC neurons send axons there.

DOI 10.1172/jci.insight.161874 · PubMed 37200091 · PMC10371239, Fig. 6D–F

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.