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Mouse

sAMY (Striatum-like amygdalar nuclei) projects to PAG (Periaqueductal gray)

4 claims from 2 sources: 4 found, 0 tested and absent, 0 ambiguous. Evidence: anterograde tracer, retrograde tracer. Strongest reported: strong.

The claims behind it

clm-70km6yteebpresentretrograde tracerproposed

AAV-retro-Cre injected into the caudolateral PAG together with a Cre-dependent fluorophore in the amygdala labelled cell bodies in the central-medial boundary zone, showing these neurons project to the PAG; about 92% of them expressed VGAT.

DOI 10.7554/elife.63493 · PubMed 33372655 · PMC7793624, Fig. 4A; Fig. 4—figure supplements 1–2

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

clm-k1w4q75618presentanterograde tracerstrength: strongproposed

tdTomato/ChR2 labelling of PAG-projecting amygdalar central-medial boundary neurons revealed dense axon terminal fields in the caudolateral PAG overlapping those of POAPAG neurons.

DOI 10.7554/elife.63493 · PubMed 33372655 · PMC7793624, Fig. 2—figure supplement 3 (bottom right); Fig. 5B

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

clm-qzv8yj5mbhpresentanterograde tracerproposed

Cre-dependent tdTomato injected into the amygdala of Esr1-Cre mice revealed labeled axons in the caudolateral PAG region containing PAG-USV neurons.

DOI 10.7554/elife.85547 · PubMed 37314164 · PMC10353859, Fig. 3C

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

clm-zq56bj6eskpresentretrograde tracerproposed

Injecting AAVretro-Cre into caudolateral PAG plus Cre-dependent virus in the amygdala labeled PAG-projecting neurons in the AmgC/M but not the CeA of female mice; these neurons were all VGAT-positive.

DOI 10.7554/elife.85547 · PubMed 37314164 · PMC10353859, Fig. 2B; Fig. 2E

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.