Skip to content

Mouse

BLA (Basolateral amygdalar nucleus) functionally connects to CA (Ammon's horn)

1 claim from 1 source: 1 found, 0 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping.

The claims behind it

clm-js6crcms0gpresentoptogenetic circuit mappingproposed

Light pulses delivered in the ventral hippocampus after ChR2 expression in the BLA produced only short-latency evoked potentials, consistent with direct axonal input, detectable about 11 days after injection. Local infusion of the AMPA-receptor antagonist CNQX through the probe suppressed the optically evoked response and abolished the stimulation-induced behavioural change, indicating a glutamatergic synaptic connection.

DOI 10.1038/nn.4510 · PubMed 28218915 · PMC5374019, Fig. 3k, 3o; Supplementary Fig. 10

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5-5) is unsure. “Short-latency vHPC responses and the CNQX block of the behavioural effect are reported, but the text never states that CNQX suppressed the evoked potentials, which leaves the excitatory sign only indirectly supported.”