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Mouse

ACA (Anterior cingulate area) projects to BLA (Basolateral amygdalar nucleus)

4 claims from 3 sources: 4 found, 0 tested and absent, 0 ambiguous. Evidence: anterograde tracer, retrograde tracer. Strongest reported: strong.

The claims behind it

clm-ghdkg1jzwqpresentanterograde tracerproposed

AAV-driven ChR2-EYFP expression in the anterior cingulate cortex led to labelled axon terminals in the basolateral amygdala several weeks after injection.

DOI 10.1038/s41398-020-0837-3 · PubMed 32424318 · PMC7235080, Results, prefrontal-amygdala pathways; Supplementary Fig. 1A

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

clm-h2yh32ew7qpresentanterograde tracerproposed

Rostral cingulate injections labelled mainly the periventricular and inner intermediate strata of the medial basolateral subdomain, without clear superficial labelling.

DOI 10.1007/s12035-026-06153-8 · PubMed 42642694 · PMC13506595, Fig. 2k–m; Table 1

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

clm-tm13c738kzpresentretrograde tracerproposed

CAV2-Cre injected into the BLA, combined with Cre-dependent eYFP in the ACC, labelled ACC neurons mainly in layer V on the same side, with fewer labelled neurons in the opposite ACC, in all five mice.

DOI 10.1038/s41467-018-05090-y · PubMed 30013065 · PMC6048069, Fig. 5d-f; Fig. 6b

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

clm-xsfqdyjwhkpresentanterograde tracerstrength: strongproposed

Expressing the presynaptic marker eGFP-Syb2 in caudal ACC neurons gave strong labelled terminals in the BLA in all three mice, making it the main amygdala target. Most Syb2 puncta in the BLA co-localized with VGLUT1 rather than VGAT.

DOI 10.1038/s41467-018-05090-y · PubMed 30013065 · PMC6048069, Fig. 5a-c, g-h

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.