Mouse
BLAp (Basolateral amygdalar nucleus, posterior part) functionally connects to ILA (Infralimbic area)
3 claims from 1 source: 2 found, 1 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping.
The claims behind it
In triplet recordings, train stimulation of cBLA fibres that reliably spiked IL layer 5 pyramidal tract neurons never produced action potentials in IL layer 5 or layer 2 cortico-amygdalar neurons (7 triplets, 4 animals), so cBLA does not functionally drive the reciprocal cortex-to-amygdala cells.
DOI 10.7554/elife.82688 · PubMed 36476757 · PMC9803354, Fig. 5—figure supplement 1Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.
Optical stimulation of cBLA axons evoked monosynaptic glutamatergic currents that were much larger in IL layer 5 pyramidal tract neurons than in any other recorded cell type, mapped to perisomatic and basal dendrites, and drove nearly every stimulus to spike (firing probability 0.98 ± 0.02, 7 pairs). Responses were also larger at IL L5 PT than at neighbouring IL L5 cortico-amygdalar neurons.
DOI 10.7554/elife.82688 · PubMed 36476757 · PMC9803354, Fig. 2D, 2E–F; Fig. 3C,D,F; Fig. 2—figure supplement 1D–FMade by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.
Stimulating cBLA in awake mice mainly altered firing in IL layer 5, where 26.6 percent of single units responded and 17.7 percent were activated, with a much smaller effect in IL layer 2.
DOI 10.7554/elife.82688 · PubMed 36476757 · PMC9803354, Fig. 4C,E,G; Fig. 4—figure supplements 1 and 2Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.