Mouse
BLAp (Basolateral amygdalar nucleus, posterior part) functionally connects to PL (Prelimbic area)
3 claims from 1 source: 2 found, 1 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping.
The claims behind it
Monosynaptic currents from cBLA axons onto PL layer 5 pyramidal tract neurons were essentially nil (under one percent of the IL L5 PT response), and even stimulation strong enough to make IL L5 PT neurons fire evoked no excitatory current in PL L5 PT neurons (9 pairs, 3 animals), only a trace of inhibition.
DOI 10.7554/elife.82688 · PubMed 36476757 · PMC9803354, Fig. 2D; Fig. 5G–IMade by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.
cBLA stimulation produced only few responsive units in PL in vivo: 2.6 percent of layer 2 units and 12.9 percent of layer 5 units changed firing, far below the effect in IL layer 5.
DOI 10.7554/elife.82688 · PubMed 36476757 · PMC9803354, Fig. 4E,G; Fig. 4—figure supplements 1 and 2Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.
cBLA axon stimulation produced only very small monosynaptic excitatory currents in PL layer 2 cortico-amygdalar neurons (about six percent of the IL L5 PT amplitude; EPSC1 -31 ± 10 pA with trains), negligible inhibition, and never evoked action potentials in these cells (firing probability 0, 7 pairs).
DOI 10.7554/elife.82688 · PubMed 36476757 · PMC9803354, Fig. 2D; Fig. 3C,D,FMade by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.