Mouse

MEA (Medial amygdalar nucleus) functionally connects to MEA GABAergic neurons

1 claim from 1 source: 1 found, 0 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping.

The claims behind it

clm-1c0e4e0a9xpresentoptogenetic circuit mappingproposed

In UCN3-Cre::VGAT-Flpo mice expressing Chrimson in MePD UCN3 neurons and GCaMP6s in MePD GABA neurons, pulsed 10 Hz optogenetic activation of the UCN3 cells (with UCN3-co-expressing GABA cells removed from analysis) changed the calcium activity and pairwise correlation structure of the GABA population relative to baseline and to non-opsin controls, splitting GABA cells into two anti-correlated clusters; 5 Hz stimulation produced no significant change while 10 Hz did.

DOI 10.1038/s41467-026-70364-9 · PubMed 41807404 · PMC13319269, Fig. 1A, H–K; Fig. 2A, B

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