Mouse

MPO (Medial preoptic area) projects to sAMY (Striatum-like amygdalar nuclei)

3 claims from 2 sources: 3 found, 0 tested and absent, 0 ambiguous. Evidence: anterograde tracer, retrograde tracer.

The claims behind it

clm-3sw6env1k4presentanterograde tracerproposed

GFP-labelled axons from PAG-projecting preoptic neurons were found in the amygdalar central-medial boundary zone, overlapping the cell bodies of AmgC/M-PAG neurons.

DOI 10.7554/elife.63493 · PubMed 33372655 · PMC7793624, Fig. 2—figure supplement 3 (middle left)

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

clm-d12r90m1knpresentanterograde tracerproposed

Cre-dependent GCaMP8s expressed in POA of Esr1-Cre males labeled axon terminals in the AmgC/M, from which terminal calcium activity was recorded.

DOI 10.7554/elife.85547 · PubMed 37314164 · PMC10353859, Fig. 5A

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) disagrees. “Fig. 5A is a viral schematic for fiber photometry of terminal calcium activity, not an anterograde tracing result.”

clm-vb56mrk64mpresentretrograde tracerproposed

AAVretro-Cre injected into the AmgC/M with Cre-dependent GFP in POA labeled POA cells projecting to the AmgC/M, most of which were Esr1-positive (298 of 362).

DOI 10.7554/elife.85547 · PubMed 37314164 · PMC10353859, Fig. 6A-B

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.