Mouse
TH (Thalamus) functionally connects to LA (Lateral amygdalar nucleus)
4 claims from 2 sources: 4 found, 0 tested and absent, 0 ambiguous. Evidence: electrical stimulation, optogenetic circuit mapping.
The claims behind it
In amygdala slices, optical activation of ChrimsonR-expressing thalamic axons evoked AMPA receptor-mediated synaptic currents in lateral amygdala neurons recorded in whole-cell mode (with GABA-A and NMDA receptors blocked); co-illumination with yellow light suppressed these responses.
DOI 10.7554/elife.91421 · PubMed 39023519 · PMC11257676, Figure 2a-cMade by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.
Blue light pulses on oChIEF- or ChrimsonR-expressing thalamic axons evoked field EPSPs recorded in the lateral amygdala of anesthetized mice; these responses were potentiated by high-frequency optical stimulation and were abolished by the AMPA receptor blocker NBQX and by TTX, showing a glutamatergic synaptic connection.
DOI 10.7554/elife.91421 · PubMed 39023519 · PMC11257676, Figure 1c,d; Figure 2fMade by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.
Internal capsule stimulation evoked excitatory currents in GAD67-GFP lateral amygdala interneurons recorded together with neighbouring principal neurons.
DOI 10.3389/fncel.2019.00220 · PubMed 31164805 · PMC6536628, Fig. 1E; Fig. 2D; Supplementary Fig. 1Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.
Electrical stimulation of internal capsule (thalamic) afferent fibres in lateral amygdala slices evoked EPSPs in putative pyramidal cells, and weak tetanic stimulation produced a transient potentiation of these responses.
DOI 10.7554/elife.91421 · PubMed 39023519 · PMC11257676, Figure 5d-fMade by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.