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ILA2/3 (Infralimbic area, layer 2/3) functionally connects to ILA5 (Infralimbic area, layer 5)

2 claims from 1 source: 1 found, 0 tested and absent, 1 ambiguous. Evidence: optogenetic circuit mapping.

The claims behind it

clm-k73k9tf59spresentoptogenetic circuit mappingproposed

Among BLA-projecting ventral mPFC cells, stimulating layer 2 and layer 3 cells produced connections onto layer 5 BLA-projecting cells.

DOI 10.1038/s41467-023-37318-x · PubMed 36966143 · PMC10039875, Fig. 3d

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

clm-mnfaa2pra5ambiguousoptogenetic circuit mappingproposed

No input from layer 2 or 3 random cells was detected onto layer 5 random cells, nor from layer 2/3 mPFC-BLA cells onto layer 5 non-mPFC-BLA cells. The authors note this may reflect the small number of such maps.

DOI 10.1038/s41467-023-37318-x · PubMed 36966143 · PMC10039875, Fig. 3d

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.