Mouse

ACB (Nucleus accumbens) projects to LHA (Lateral hypothalamic area)

2 claims from 1 source: 2 found, 0 tested and absent, 0 ambiguous. Evidence: anterograde tracer, retrograde tracer.

The claims behind it

clm-wrrctr6te5presentanterograde tracerproposed

Cre-dependent AAV-mCherry injected into the NAc of NPY-Cre mice labelled many punctate fibres in the anterior and posterior LH. A synaptophysin-EGFP AAV also produced EGFP presynaptic puncta in the LH, so the authors conclude that accumbal NPY neurons project mainly to the LH.

DOI 10.3389/fnana.2021.741868 · PubMed 34566585 · PMC8460764, Figs. 2 and 3

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

clm-zwdzadd5nxpresentretrograde tracerproposed

CTb injected into the LH retrogradely labelled ipsilateral NAc neurons, about 7% of them mCherry-labelled NPY neurons. In a second experiment, EnvA-pseudotyped rabies injected into the LH infected TVA-expressing NAc NPY neurons, labelling about 9.6% of the NPY neurons.

DOI 10.3389/fnana.2021.741868 · PubMed 34566585 · PMC8460764, Fig. 4, Table 1; Fig. 5, Table 2

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) disagrees. “The 7.19% is the share of mCherry NPY neurons that were CTb-positive, not the share of CTb-labelled neurons that were NPY, so the paraphrase reverses the ratio.”