Mouse

VTA (Ventral tegmental area) projects to ACB (Nucleus accumbens)

1 claim from 1 source: 1 found, 0 tested and absent, 0 ambiguous. Evidence: retrograde tracer.

The claims behind it

clm-5z80a358n0presentretrograde tracerproposed

Retrograde AAV encoding tdTomato (AAVrg-CAG-tdTomato in wild-type mice, AAVrg-FLEX-tdTomato in TH-BAC-Cre mice) injected into the nucleus accumbens retrogradely labelled VTA neurons, including dopaminergic ones. When combined with a differently coloured retrograde tracer in the BLA, only about 2.7% of 2100 labelled VTA neurons carried both labels, indicating largely segregated VTA→NAc and VTA→BLA populations.

DOI 10.1038/s41467-022-29155-1 · PubMed 35318315 · PMC8940900, Supplementary Fig. 3a, b; Results (VTA → BLA dopamine neuron hypoactivity section)

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.