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LC (Locus ceruleus) functionally connects to VTA (Ventral tegmental area)

1 claim from 1 source: 1 found, 0 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping.

The claims behind it

clm-qdga0y8c9wpresentoptogenetic circuit mappingproposed

Optogenetic 10-Hz phasic activation of ChR2-expressing locus coeruleus neurons paired with an odor raised the number of cFos-positive cells in the ventral tegmental area and the fraction of tyrosine-hydroxylase-positive VTA neurons expressing cFos, relative to odor-only controls; 10-Hz tonic activation of the same site produced no such increase.

DOI 10.1093/texcom/tgab026 · PubMed 34296171 · PMC8152946, Fig. 4D–H

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); not checked yet.