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CEA (central amygdaloid nucleus) functionally connects to VTA (Ventral tegmental area)

1 claim from 1 source: 1 found, 0 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping.

The claims behind it

clm-bepbbgd3fvpresentoptogenetic circuit mappingproposed

Optogenetic ChR2 excitation of CeA paired with reward or shock-rod encounters was followed by strongly raised Fos protein counts in the ventral tegmental area (over 800% above baseline in the sucrose/cocaine group, over 400% above eYFP controls in the shock-rod group, mainly in the caudal VTA), indicating that CeA activation drives activity in VTA, although the effect may be indirect and behaviourally mediated.

DOI 10.1038/s41467-020-16407-1 · PubMed 32483118 · PMC7264246, Results, 'Shock-rod attraction activates mesocorticolimbic circuity'; Fig. 5; Supplementary Table 1

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.