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AI (Agranular insular area) projects to BLA (basal amygdaloid nucleus)

2 claims from 2 sources: 2 found, 0 tested and absent, 0 ambiguous. Evidence: retrograde tracer.

The claims behind it

clm-gpf73z0tehpresentretrograde tracerproposed

A retrograde AAV2-retro tracer injected into the basolateral amygdala labelled neurons in the anterior agranular insula; these accounted for 34% of the labelled amygdala-projecting insular neurons. Projection-specific DREADD expression using retrograde Cre injected into the BLA also demonstrated this insula-to-BLA pathway.

DOI 10.3389/fnbeh.2020.580849 · PubMed 33328918 · PMC7671963, Figs. 5A–C; Fig. 4B

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

clm-wn9cmwejnzpresentretrograde tracerproposed

Agranular insular cortex contained FG-labeled neurons, somewhat more than the sparse labeling in dysgranular insula, after BLpc injection.

DOI 10.3389/fncir.2025.1575232 · PubMed 40352758 · PMC12061975, Fig. 3B–J, 4B,F

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.