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BLA glutamatergic principal neurons projects to ACA (Anterior cingulate area)

2 claims from 2 sources: 2 found, 0 tested and absent, 0 ambiguous. Evidence: anterograde tracer, retrograde tracer. Strongest reported: strong.

The claims behind it

clm-2kp086e8b3presentretrograde tracerproposed

A retrograde AAV-Cre-mCherry injected into the ACC of GAD67-GFP mice labelled BLA cell bodies. These cells did not overlap with GAD67-GFP neurons and co-expressed Vglut2 mRNA, so the BLA-to-ACC projection neurons are glutamatergic.

DOI 10.3389/fncel.2022.1070015 · PubMed 36619672 · PMC9813383, Fig. 3C-E

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

clm-d3803ga47hpresentanterograde tracerstrength: strongproposed

After injecting a CaMKIIα-driven ChR2-mCherry virus into the BLA, labelled axons were found in large numbers in layers II/III of the anterior cingulate cortex; a separate chemogenetic virus injected in BLA likewise filled many mCherry-positive terminals in ACC.

DOI 10.7150/thno.111130 · PubMed 40225572 · PMC11984391, Fig. 6A; Fig. S2E

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.