The medial prefrontal cortex to the medial amygdala connections may affect the anxiety level in aged rats

PL (Prelimbic area) UBERON:8440032 projects to MEA (medial amygdaloid nucleus) UBERON:0002892 · Rat

After Fluoro-Gold injection into the MeA, labelled cells appeared bilaterally in prelimbic cortex across all cortical layers. The paper graded this labelling from moderate in young males to very strong in young females and old males.

Results, Tables 1 and 2, Figs. 3-5

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

ACA (Anterior cingulate area) UBERON:0009835 projects to MEA (medial amygdaloid nucleus) UBERON:0002892 · Rat

Fluoro-Gold injected into the right or left MeA retrogradely labelled neurons in the cingulate cortex of both hemispheres, mainly in deep layers. Labelling was graded from weak in young males to very strong in young females and old rats.

Results, Tables 1 and 2, Figs. 3-5

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

ILA (Infralimbic area) UBERON:8440033 projects to MEA (medial amygdaloid nucleus) UBERON:0002892 · Rat

MeA tracer injections labelled infralimbic neurons in both hemispheres, scattered across all layers. Labelling was generally weaker than in Cg and Pl, graded weak to strong depending on age and sex group.

Results, Tables 1 and 2, Figs. 3-5

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.